ENGINEERED TRX2P INDUSTRIAL YEAST STRAIN PROTECTS GLYCOLYSIS AND FERMENTATION PROTEINS FROM OXIDATIVE CARBONYLATION DURING BIOMASS PROPAGATION

Engineered Trx2p industrial yeast strain protects glycolysis and fermentation proteins from oxidative carbonylation during biomass propagation

Abstract Background In the yeast biomass production process, protein carbonylation has severe adverse effects since it diminishes biomass yield and profitability of industrial production plants.However, this significant detriment of yeast performance can be alleviated by increasing thioredoxins levels.Thioredoxins are important antioxidant defenses

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The position of DNA cleavage by TALENs and cell synchronization influences the frequency of gene editing directed by single-stranded oligonucleotides.

With recent technological advances that enable DNA cleavage at specific sites in the human genome, it may now be possible to reverse inborn errors, thereby correcting a mutation, at levels that could have an impact in a clinical setting.We have been developing gene editing, using single-stranded DNA oligonucleotides (ssODNs), as a tool to direct si

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